Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00633Dexrazoxane--
BADD_D00634Dexrazoxane hydrochloride--
BADD_D00646Diatrizoate sodium--
BADD_D00647Diatrizoic acid--
BADD_D00648Diazepam--
BADD_D00649Diazoxide--
BADD_D00653Diclofenac--
BADD_D00668Digoxin--
BADD_D00674Diltiazem--
BADD_D00675Diltiazem hydrochloride--
BADD_D00680Dimethyl fumarate--
BADD_D00683Dinoprost tromethamine--
BADD_D00684Dinoprostone--
BADD_D00686Diphenhydramine--
BADD_D00692Dipyridamole--
BADD_D00696Divalproex sodium--
BADD_D00699Docetaxel0.004263%
BADD_D00701Dofetilide0.002225%
BADD_D00702Dolasetron--
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00711Dornase alfa--
BADD_D00716Doxapram--
BADD_D00717Doxapram hydrochloride--
BADD_D00718Doxazosin--
BADD_D00719Doxazosin mesylate--
BADD_D00720Doxepin--
BADD_D00722Doxercalciferol0.036851%
BADD_D00723Doxorubicin--
BADD_D00724Doxorubicin hydrochloride--
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